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. 2021 Feb 11;12:625236. doi: 10.3389/fgene.2021.625236

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Copyright © 2021 Liu, Yu, Liu, Zou, Zhou, Hu and Song.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression profiles and biological functions of stromal and immune score–related DEGs. (A,B) Heatmaps showing expression profiles for selected stromal score (right) and immune score (left)–related DEGs (Log2 fold change ≥ 3 and adjusted P < 0.05) with unsupervised hierarchical clustering analyses, using the complete linkage method to measure distances between clusters. (C) Shows the commonly upregulated DEGs, and (D) shows the commonly downregulated DEGs. (E) The top 10 of biological processes GO terms (top), cellular component GO terms (middle), and molecular function GO terms (bottom); (F) KEGG (Kyoto Encyclopedia of Genes and Genomes) analysis of microenvironment-related DEGs.