Table 4.
Cox proportional hazard regression analysis.
| Variable | HR | 95%CI | P-value | |
|---|---|---|---|---|
| Lower | Upper | |||
| Sex | ||||
| Male | 1 | |||
| Female | 0.659 | 0.379 | 1.148 | 0.141 |
| Age at onset | 1.014 | 0.988 | 1.040 | 0.288 |
| Onset site | ||||
| Bulbar | 1 | |||
| Upper-limb | 0.814 | 0.316 | 2.094 | 0.669 |
| Lower-limb | 0.500 | 0.178 | 1.401 | 0.187 |
| Airlie house category | ||||
| Clinically definite | 1 | . | ||
| Clinically probable | 1.411 | 0.679 | 2.932 | 0.356 |
| Laboratory-supported probable | 1.415 | 0.653 | 3.065 | 0.379 |
| Clinically possible | 2.110 | 0.855 | 5.205 | 0.105 |
| Suspected | 1.334 | 0.286 | 6.226 | 0.714 |
| ALSFRS-R | 0.929 | 0.878 | 0.984 | 0.012a |
| CMAP-12 | ||||
| Normal | 1 | |||
| Mild | 1.924 | 0.715 | 5.178 | 0.195 |
| Moderate | 3.394 | 1.292 | 8.917 | 0.013a |
| Severe | 4.732 | 2.032 | 11.017 | 0.000b |
a
p ≤ 0.05,
b
p ≤ 0.01; HR, Hazard Ratio; CI, Confidence Interval.