2.
Laboratory results of COVID-19 patients on admission according to acute kidney injury status
| Parameter | Normal range | Total (n=287) | AKI (n=55) | No AKI (n=232) | P |
| Data are presented as median with interquartile range (IQR) in parenthesis unless specified otherwise. AKI: Acute kidney injury. CT: Computed tomography. NA: Not applicable. 1By PCR tests for influenza A virus, influenza B virus, rhinovirus/enterovirus, respiratory syncytial virus A/B, adenovirus, Mycoplasma pneumoniae, parainfluenza viruses, Bordetella pertussis, Legionella pneumophila, and Chlamydophila pneumoniae. 2For each patient, the initial CT scans were evaluated and a quantitative score was assigned based on characteristics reported in recently published literature[9]. | |||||
| White blood cell count (×109/L) | 4.0-10.0 | 5.0 (3.8-7.2) | 5.8 (4.3-9.5) | 4.9 (3.6-6.7) | < 0.01 |
| < 4 [n(%)] | - | 129(45) | 9(16) | 120 (52) | |
| 4-10 [n(%)] | - | 131 (46) | 34 (62) | 97 (42) | < 0.01 |
| >0 [n(%)] | - | 27(9) | 12(22) | 15(6) | |
| Neutrophil count (×109/L), | 1.8-6.3 | 3.6 (2.3-5.5) | 4.5 (3.0-8.5) | 3.4 (2.2-5.1) | < 0.01 |
| Lymphocyte count (×109/L), | 1.1-3.2 | 0.8 (0.6-1.2) | 0.7 (0.4-1.0) | 0.9 (0.6-1.2) | < 0.01 |
| Hemoglobin (g/L, Mean±SD) | 120-150 | 128.3±17.1 | 125±20.0 | 129.1±16.3 | 0.11 |
| Prothrombin time (s, Mean±SD) | 11.0-16.0 | 15.3±5.8 | 17.1±11.7 | 14.9±2.8 | 0.11 |
| Activated partial thromboplastin time (s, Mean±SD) | 27.0-45.0 | 35.8±7.3) | 37.7±10.5 | 35.4±6.3 | 0.05 |
| D-dimer (mg/mL) | 0.0-0.5 | 0.6 (0.2-2.0) | 0.9 (0.2-6.6) | 0.5 (0.2-1.6) | < 0.01 |
| Alanine aminotransferase (U/L) | 0-40 | 25(17-38) | 27(18-43) | 24(16-37) | 0.18 |
| Aspartate aminotransferase (U/L) | 0-40 | 27(20-41) | 35 (23-50) | 26(19-40) | < 0.01 |
| Total bilirubin (μmol/L) | 3.4-20.5 | 8.9(6.6-12.0) | 11.0(8.1-16.0) | 8.6(6.3-11.38) | < 0.01 |
| Albumin (g/L, Mean±SD) | 34.0-54.0 | 33.4±4.8 | 31.6±5.6 | 33.8±4.5 | < 0.01 |
| Creatine kinase (U/L) | 30.0-310.0 | 100.0(58.0-172.0) | 118.0(69.0-223.0) | 99.0(51.25-154.0) | 0.03 |
| Lactate dehydrogenase (U/L) | 120-150 | 255(188-359) | 344 (234-469) | 238(183-333) | < 0.01 |
| Glucose>11.1 mmol/L [n(%)] | 3.9-6.1 | 44(15.0) | 12(22.0) | 32(14.0) | 0.14 |
| Procalcitonin (ng/mL) | < 0.05 | 0.07(0.05-0.16) | 0.15(0.09-0.41) | 0.07 (0.04-0.13) | < 0.01 |
| C-reactive protein (mg/L) | ≤5.0 | 23.4(4.1-38.0) | 34.6(10.6-71.7) | 19.5(4.0-37.0) | 0.02 |
| Hyperkalemia (>5.0 mmol/L) [n(%)] | ≤5 | 22 (8.0) | 10(18.0) | 12(5.0) | < 0.01 |
| Other respiratory pathogens1 [n(%)] | NA | 4(1.0) | 0(0.0) | 4(2.0) | >0.99 |
| CT score2 | NA | 7(5-12) | 9(6-15) | 7(5-11) | < 0.01 |