4.
安罗替尼联合替吉奥治疗26例复发转移性食管鳞癌患者的主要不良反应
Treatment-related adverse effects of anlotinib plus S-1 treatment in the 26 patients (number of cases)
| Adverse effects | Ⅰ | Ⅱ | Ⅲ | Ⅳ | In total |
| Fatigue | 7 | 3 | 0 | 0 | 10 |
| Hypertension | 6 | 1 | 1 | 0 | 8 |
| Hand-foot syndrome | 6 | 2 | 0 | 0 | 8 |
| Proteinuria | 3 | 1 | 0 | 0 | 4 |
| Abnormal liver function | 3 | 0 | 0 | 0 | 3 |
| Diarrhea | 2 | 0 | 0 | 0 | 2 |