Figure 1.

Time course depicting the clinical presentation of IgG4RD, laboratory results and treatment plans from 2009 to 2020. Chronic phase of the patient’s disease: the upper part summarizes the specific features of clinical findings, biopsy, imaging, and immunological laboratory results; the lower part shows the therapy, specifying dose, duration, and dates for Rituximab infusions (deep red diamonds) and steroids (sky blue bars). Pulse treatment with methyl-prednisone (500mg i.v.) is represented by the bottom scale blue bars and was usually followed by oral Prednisone (top scale blue bars); the dashed bar corresponds to the period when the patient did not adhere thoroughly to the prescribed therapy.