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. 2021 Feb 11;11:604759. doi: 10.3389/fimmu.2020.604759

Figure 2.

Figure 2

In the acute phase, the upper part shows the laboratory values for CFH (black, μg/ml), anti-CFH (pink, AU/ml), left y-axis, and thrombocytes (green, G/l) at the right y-axis. The normal reference values are shown with shades matching the colors of the different parameters. The lower part depicts the therapy including methylprednisolone/prednisone (sky blue bars, mg/d), plasma exchanges (deep blue arrows), and cyclophosphamide (purple triangles, 500 mg i.v.). The time when TMA and COVID-19 were diagnosed are shown with symbols. AU, arbitrary units; BM, bone marrow; Covid-19; coronavirus disease 2019; CT, computed tomography; CTX, cyclophosphamide; HPF, high-power field; IgA, immunoglobulin A; IgG4-RD, immunoglobulin G4-related disease; i.v., intra venous; PET-CT, positron emission tomography-computed tomography; PLEX, plasma exchange; RTX, Rituximab; SARS-CoV-2 severe acute respiratory syndrome coronavirus 2; TMA, thrombotic microangiopathy.