Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 17;21(4):297. doi: 10.3892/ol.2021.12558

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — Knockdown of FAM83A inhibits the malignant phenotype of LUAD in NCIH1650 cells. (A) Expression plot FAM83A in multiple cancer cell lines. (B) Expression of FAM83A in some lung_NSC cells and the common LUAD cell line NCIH1650 was chosen for further research. (C) Transfection efficiency of siRNAs were confirmed using reverse transcirption-quantitative PCR and western blotting. (D) EdU (magnification, ×400) and (E) CCK-8 assays indicated that silencing FAM83A suppressed proliferation of NCIH1650 cells. (F) Transwell (×400) and (G) Matrigel (magnification, ×400) assays suggested that knockdown of FAM83A inhibited migration and invasion of NCIH1650 cells. ***P<0.001 vs. si-NC. lung_NSC, non-small cell lung cancer; CCK-8, Cell Counting Kit-8; si, small interfering; NC, negative control.