Table 3.

Summary of treatment-related AEs^a

	Treatment-related AEs of all grades	Grade 3–4 treatment-related AEs
	Patients, n (%)	Patients, n (%)
Nausea	22 (28)	2 (3)
Edema peripheral	21 (26)	0
Headache	17 (21)	0
Pyrexia	16 (20)	1 (1)
Capillary leak syndrome	7 (9)	2 (3)
Hemolytic uremic syndrome	6 (8)	4 (5)
Lymphocyte count decreased	6 (8)	6 (8)
Anemia	5 (6)	2 (3)
Platelet count decreased	5 (6)	2 (3)
Hypertension	4 (5)	2 (3)
Acute kidney injury	2 (3)	2 (3)
Neutropenia	2 (3)	2 (3)
White blood cell count decreased	2 (3)	2 (3)

AE adverse event

^aAdverse events of any grade with an incidence of at least 20%, as well as events of grade 3 or 4 with an incidence of at least 3%