Table 1.
Demographics, clinical and oral conditions of subjects (n = 50)
| Crohn's disease (CD) | Healthy controls (HC) | |
|---|---|---|
| Mean age* (Range) | 40 (23–67) | 40 (21–66) |
| Race | ||
| Han Chinese | 13 | 13 |
| Malay | 3 | 3 |
| Indian | 9 | 9 |
| Sex | ||
| Male | 10 | 10 |
| Female | 15 | 15 |
| Oral condition | ||
| Mean DMFT^ | 6.5 ± 7.0 | 4.6 ± 5.0 |
| Periodontitis present | 5 | 5 |
| Smoking | ||
| Non-smoker | 20 | 21 |
| Previous/current smoker | 5 | 4 |
| CD condition | ||
| Length of diagnosis in years (range) | 7.8 (1–20) | |
| Crohn’s Disease Activity Index (CDAI) | 86.2 ± 87.1 | |
| Current disease activity: Active (Diarrhoea, Abdominal pain, Blood-in-stool, fever and fatigue) | 10 | |
| Drug regimen# | ||
| Steroids/Anti-inflammatory (Mesalazine) | 8 | |
| Azathioprine | 13 | |
| Biologics | 11 | |
| Others (Tacrolimus, sulphasalazine) | 2 | |
*Matched controls are ± 3 years
^p-value = 0.29
#some subjects are on multiple drug regimen