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. 2021 Feb 25;13:13. doi: 10.1186/s13099-021-00409-5

Table 3.

Clinical characteristics of subjects with concordant gut and oral S. salivarius strains

CD subjects with concordant strains (n = 4) CD subjects with no concordant strain (n = 21) p-value
Crohn’s Disease Activity Index (CDAI)# 184.3 ± 2.9 67.1 ± 82.5 *0.012
Disease status
 Active disease at time of sampling (Diarrhoea/abdominal pain/blood-in-stool/fever and fatigue) 4 6 *0.016
 Inactive disease at time of sampling 0 15
Proton Pump Inhibitor use 1.000
 Yes 1 7
 No 3 14
Mean age# 38 ± 14 40 ± 14 0.774
Race 0.056
 Han Chinese 4 9
 Malay 0 3
 Indian 0 9
Sex 0.142
 Male 3 7
 Female 1 14
Oral condition 0.661
 DMFT# 5.0 ± 4.2 6.8 ± 7.4
Periodontitis 0.451
 Present 1 4
 Absent 3 17

All Fisher-Exact test except #T-test

*p-value < 0.05