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. 2021 Feb 10;21(4):278. doi: 10.3892/ol.2021.12539

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Copyright: © Tanio et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — AMIGO2 expression on colorectal cancer cells and sites of metastasis. Increased AMIGO2 expression was significantly associated with increased frequency of (A) liver metastasis, but not (B) pulmonary metastasis and (C) peritoneal metastasis. (D) Increased AMIGO2 expression was significantly associated with increased frequency of metachronous liver metastasis in all patients. Increased AMIGO2 expression was significantly associated with increased frequency of metachronous liver metastasis in (E) node-negative patients, but not in (F) node-positive patients. χ² test was used for all statistical analysis. AMIGO2, adhesion molecule with Ig like domain 2.