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. 2021 Feb 10;21(4):278. doi: 10.3892/ol.2021.12539

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Copyright: © Tanio et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Representative images of AMIGO2 expression in (A) primary lesion (A) and (B) liver metastatic lesion obtained from the same patient. (C) The intensity of AMIGO2 staining was significantly stronger in the tissue obtained from liver metastasis of CRC compared with the primary lesion (n=21). The Wilcoxon test was used for the statistical analysis. (D) Kaplan-Meier analysis of overall survival in colon cancer patients with high (≥2.97 FPKM) vs. low AMIGO2 (<2.97 FPKM) mRNA expression. The cut-off value was according to FPKM provided by The Human Protein Atlas. The differences between survival curves were examined using the log-rank test. FPKM, fragments per kilobase of exon per million reads mapped. AMIGO2, adhesion molecule with Ig like domain 2.