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. 2021 Feb 25;19:59. doi: 10.1186/s12916-021-01925-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Associations of genomic mutations and molecular subtypes in glycolysis-associated long noncoding (lnc)RNA-classified clusters. a A heatmap showing gene candidates with nonsilent mutations enriched in certain clusters of bladder carcinoma (BLCA), pancreatic ductal adenocarcinomas (PAADs), uveal melanomas (UVMs), and low-grade gliomas (LGGs). b Alluvial plots demonstrating comparisons of lncRNA-stratified subgroups (lnc cluster) with tumor grade (grade) and molecular subtypes (subtype) in BLCA, LGG, mesotheliomas (MESO), PAAD, and UVM. ND, not determined; BS, basal/squamous; LUM, luminal-like; Lum-inf, luminal infiltrated; Lum pap, luminal papillary; Neu, neuroendocrine-like; PN, proneural; NE, neural; CL, classical; ME, mesenchymal