Table I.
Basic clinical characteristics of patients with HPV-negative (n=27) and HPV-positive (n=35) HNSCC.
| Clinicopathological feature | HPV-negative HNSCC | HPV-positive HNSCC | P-value |
|---|---|---|---|
| Mean age ± SD, years | 71.4±6.7 | 72.4±7.3 | >0.05 |
| Sex, n (%) | >0.05 | ||
| Male | 12 (44.4) | 17 (48.5) | |
| Female | 15 (55.6) | 18 (51.5) | |
| Tumor grade (Broders), n (%) | >0.05 | ||
| Grade I | 12 (44.4) | 16 (45.7) | |
| Grade II | 13 (48.1) | 16 (45.7) | |
| Grade III | 2 (7.5) | 3 (9.6) | |
| Metastasis at diagnosis, n (%) | >0.05 | ||
| Yes | 2 (7.5) | 4 (11.4) | |
| No | 25 (92.5) | 31 (88.6) | |
| Tumor subsite, n (%) | >0.05 | ||
| Oral tongue | 10 (37.0) | 13 (37.1) | |
| Buccal mucosa | 2 (7.4) | 2 (5.7) | |
| Larynx | 7 (26.0) | 9 (25.7) | |
| Oral cavity | 4 (14.8) | 5 (14.2) | |
| Floor of mouth | 4 (14.8) | 6 (17.1) |
HPV, human papillomavirus; HNSCC, head and neck squamous cell carcinoma.