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. 2021 Feb 17;21(4):300. doi: 10.3892/ol.2021.12561

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — miR-153 sensitizes SW1990 to radiation through JAG1. (A) Colony survival fraction at 14 days after 0, 2, 4 and 6 Gy radiation in miR-153-overexpressing cells with or without JAG1 treatment. (B) Cell Counting Kit-8 assay showing the percentage of viable cells after 4 Gy radiation in miR-153-overexpressing cells with or without JAG1 treatment. (C) Representative plots and (D) quantification of flow cytometry analysis showing the percentage of apoptotic cells after 4 Gy radiation in miR-153-overexpressing cells with or without JAG1 treatment. *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001 with comparisons shown by lines. miR-153, microRNA-153; JAG1, jagged canonical Notch ligand 1; NC, negative control.