Table 2. Adjusted Health Care Costs per Patient Associated With Incident Deliriuma.
| Measure | Delirium, mean (95% CI) | Mean difference | P value | |
|---|---|---|---|---|
| Yes (n = 122) | No (n = 375) | |||
| Cumulative total costs, $ | ||||
| Index hospitalization | 82 431 (70 848-95 908) | 62 104 (54 132-71 250) | 20 327 | <.001 |
| Time after discharge | ||||
| 30 d | 99 676 (85 577-116 097) | 71 599 (62 223-82 387) | 28 077 | <.001 |
| 90 d | 108 978 (90 596-131 091) | 74 644 (63 096-88 306) | 34 334 | <.001 |
| 1 y | 130 816 (105 676-161 937) | 86 525 (71 122-105 264) | 44 291 | <.001 |
| Period-specific costs, $ | ||||
| Index hospitalization | 82 431 (70 848-95 908) | 62 104 (54 132-71 250) | 20 327 | <.001 |
| Discharge to 30 d | 13 526 (8767-20 870) | 7600 (5007-11 537) | 5926 | .001 |
| 30 to 90 d | 7351 (2262-23 887) | 2467 (904-6737) | 4884 | .01 |
| 90 d to 1 y | 22 636 (11 240-45 589) | 11 780 (6032-23 005) | 10 856 | .01 |
a
Results are reported in 2019 dollars, adjusted for age, male sex, education, non-White race/ethnicity, Charlson Comorbidity Score, Informant Questionnaire on Cognitive Decline in the Elderly score >3.5 or Modified Mini-Mental State Examination score ≤77, surgical site, surgery type (total knee replacement, total hip replacement, lumbar laminectomy, cervical laminectomy, open colectomy, lower extremity revascularization, abdominal aortic aneurysm repair, laparoscopic colectomy), American Society of Anesthesiologists Physical Status Classification System score ≥3, and total costs 6 months before index hospitalization; using generalized linear models.