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. 2021 Feb 25;21(2):13. doi: 10.1007/s11882-020-00986-6

Fig 1.

Fig 1

Hypothetic pathways involved in SARS-CoV-2 invasion into the host cell. Clathrin dependent, caveola dependent, flotillin dependent, and ACE2/TMPRSS2 dependent. Once the integrity of the cell membrane has been broken, viral RNA forms an endosome into the cell’s cytoplasm and uses the cellular machinery for viral replication and assembly