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. 2021 Feb 9;6(7):4842–4849. doi: 10.1021/acsomega.0c05822

Table 1. Antiproliferative Activity against Androgen-Independent Prostate Cancer Cell Lines, DU145 and PC-3.

  cell lines/IC50 (μM)a
  cell lines/IC50 (μM)a
compounds DU145 PC-3 compounds DU145 PC-3
1 >5 >5 9 1.93 >5
2 0.45 0.53 10 >5 >5
3 0.71 0.64 11 4.38 >5
4 1.71 1.56 12 4.05 3.88
5 >5 >5 13 4.05 >5
6 3.22 3.84 14 1.69 3.13
7 >5 >5 15 >5 >5
8 >5 >5      
a

The concentration of compound that caused 50% reduction of cell growth relative to untreated cells determined by cell counting.