Figure 4.
inhibited FFA-induced expression and secretion of proinflammatory cytokines and chemokines in HAECs. Cells were stimulated with 300 μM FFAs in the presence or absence of feprazone (5, 10 μM) for 24 h. (A) mRNA levels of CCL5, IL-6, and IL-8 and (B) secretion of CCL5, IL-6, and IL-8 (***, P < 0.001 vs vehicle group; #, ##, P < 0.05, 0.01 vs FFA treatment group).