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Feprazone inhibited FFA-induced expression of MMP-2 and MMP-9 in HAECs. Cells were stimulated with 300 μM FFAs in the presence or absence of feprazone (5, 10 μM) for 24 h. (A) mRNA levels of MMP-2 and MMP-9 and (B) protein levels of MMP-2 and MMP-9 (***, P < 0.001 vs vehicle group; #, ##, P < 0.05, 0.01 vs FFA treatment group).
