TABLE 4.

Associations Between GR Sensitivity Change Over Time and Inflammation Markers at One-Month Post-IMRT

	CRP	IL1β	IL6	IL10	IL1ra	IL6sr	MCP1	TNFR2	TNFα
N	74	63	73	72	74	74	74	74	74
Delta GR AUC estimate	0.59	0.12	0.41	0.19	0.16	−0.02	−0.01	−0.02	0.1
p	<.001	.056	.001	.010	.078	.40	.81	.67	.023

GR = glucocorticoid receptor; IMRT = intensive modulated radiation therapy; CRP = C-reactive protein; IL1β = interleukin β, IL1ra = interleukin 1 receptor antagonist, IL6sr = interleukin 1 soluble receptor, MCP1 = monocyte chemoattractant protein 1, sTNFR2 = soluble tumor necrosis factor receptor 2, TNFα = tumor necrosis factor α; AUC = area under the curve.

All models were controlled for covariates of baseline inflammation markers, age, sex, marital status, smoking status, alcohol status, race, treatment, body mass index, and human papillomavirus status.