. Author manuscript; available in PMC: 2021 Apr 1.

Published in final edited form as: Int J Cardiol. 2019 Nov 6;304:116–121. doi: 10.1016/j.ijcard.2019.11.002

Table 2.

Baseline ST2 Levels and Hospitalization Rates

	HF Hospitalizations		CV Hospitalizations		Total Hospitalizations
	RR (95% CI)	P	RR (95% CI)	P	RR (95% CI)	P
Adjusted - Clinical Model
Continuous ST2 (log₂)	2.31 (1.31–4.07)	0.004	1.75 (1.26–2.44)	0.001	1.63 (1.22–2.18)	0.001
Dichotomous ST2 (>35 ng/mL)	3.56 (1.69–7.49)	0.001	2.14 (1.40–3.26)	<0.001	1.97 (1.38–2.82)	<0.001
Adjusted - Clinical Model Plus BNP
Continuous ST2 (log₂)	1.62 (0.88–2.99)	0.121	1.43 (1.01–2.02)	0.045	1.38 (1.02–1.87)	0.036
Dichotomous ST2 (>35 ng/mL)	3.03 (1.42–6.46)	0.004	1.91 (1.25–2.91)	0.003	1.83 (1.28–2.61)	0.001

Estimates calculated with negative binomial regression models. Adjusted model included age, gender, race, systolic blood pressure, left ventricular ejection fraction, presence of coronary artery disease, New York Heart Association class, diabetes mellitus, renal function, history of atrial fibrillation, medical therapy, and implantable devices. BNP: B-type natriuretic peptide; CI: confidence interval; CV: cardiovascular; HF: heart failure; RR: rate ratio