Table 2.
Cyclosporine-A induced thrombosis.
| Age/gender | Thrombosis location | Primary disease | References | Country | Study size | Article type |
|---|---|---|---|---|---|---|
| NR | DVT (n = 25), PE (n = 4), DVT with PE (n = 11) |
Renal transplantation | (90) | UK | 40/480 | Retro |
| 41 ± 12 | DVT | Renal transplantation | (91) | Switzerland | 9/97 | Pro |
| 52/M (case 1) 26/M (case 2) 32/M (case 3) 61/M (case 4) 11/M (case 5) 54/M (case 6) 45/F (case 7) |
Glomerular capillary; Renal afferent artery |
Renal transplantation (cadaver-donor) | (92) | UK | 7 | Case report |
| NA | Cyclosporine-associated arteriopathy (acute tubular necrosis; acute vasculitis; glomerular ischemia; interstitial intimate; Intima proliferation; venous thrombosis) | Renal transplantation (cadaver-donor) | (93) | USA | 16/200 | Retro |
| 36.7 ± 1.3/(49/41, M/F) | PE (n = 10), Renal vein (n = 1), DVT (n = 3), Hemorrhoidal artery (n = 3) |
Renal transplantation (cadaver-donor) | (8) | Belgium | 13/90 | Retro |
| 35.9 ± 13.8 | DVT | Renal transplantation (cadaver-donor, living-donor) | (94) | Sweden | 9/97 | Pro |
| 53/F (case 1) 33/M (case 2) 48/F (case 3) |
HUS, Glomerular capillaries, Renal artery |
Renal transplantation | (95) | Canada | 3 | Case report |
| 33/F | Glomerular capillaries | Renal transplantation (cadaver-donor) | (96) | UK | 1 | Case report |
| NA | Glomerular capillaries (Platelet microthrombi) | Renal transplantation | (97) | UK | 12/32 | Retro |
| NA | Renal artery | Renal transplantation (cadaver-donor, living-donor) | (98) | China | 1/14 | Retro |
| 6 (case 1) 6 (case 2) 17 (case 3) 48 (case 4) 53 (case 5) 51 (case 6) |
Renal vein | Renal transplantation (cadaver-donor, living-donor) | (99) | UK | 6/791 | Retro |
| NA | HUS, Glomerular capillaries | Behcet's disease | (100) | France | 2 | Case report |
| NA | CVST | SSINS | (101) | UK | 1/53 | Retro |
| 45.1 ± 12.3 | Renal vein | Renal transplantation (cadaver-donor) | (102) | UK | 16 | Pro |
| NA | Eyeground artery | Recurrent nephrotic syndrome | (103) | Japan | 1 | Case report |
| NA | CVT | Renal transplantation | (104) | Spain | 1 | Case report |
| 25.0 ± 26.4 | HUS | Renal transplantation | (105) | USA | 10/672 | Retro |
| NA | Hepatic vein | Inflammatory bowel disease and latent thrombocythemia | (106) | France | 1 | Case report |
| 19/M | CVST | Severe active UC | (5) | Japan | 1 | Case report |
| 48/F | CVST (LTS, LSS), LIJVS | Chronic UC | (4) | USA | 1 | Case report |
| NA | Thrombotic microangiopathy | SPK transplantation | (107) | Belgium | 1/102 | Retro |
| (18–55) | Pancreas graft thrombosis (n = 10), Kidney graft thrombosis (n = 1) |
SPK transplantation | (9) | Belgium | 11/102 | Pro |
| 31 ± 11 | Graft thrombosis (combined arterial and venous thrombotic occlusion, n = 5; arterial occlusion, n = 3, venous occlusion, n = 1) | SPK transplantation | (3) | Austria | 9/67 | Retro |
| 30/F | Central retinal vein | Renal transplantation (cadaver-donor) | (108) | Croatia | 1 | Case report |
| 56.7 ± 10.1 | Coronary artery | Heart transplantation | (2) | Canada | 18/129 | Retro |
| 25/M | CVST (SSS, TS) | Renal transplantation (living-donor) | (1) | Sri Lanka | 1 | Case report |
| 23/F | CVT | Neuro-Behcet's disease | (109) | Brazil | 3/40 | Retro |
| 18–64/(28/33, F/M) | Venous thrombosis | Acute steroid-refractory or dependent UC | (6) | Finland | 1/61 | Pro |
| 44/F | CVST | AA | (7) | China | 1 | Case report |
R, right; L, left; CVT, cerebral vein thrombosis; CVST, cerebral vein sinus thrombosis; CoVT, cortical vein thrombosis; SSS, superior sagittal sinus; TS, transverse sinus; DVT, deep vein thrombosis; PE, Pulmonary emboli; SPK transplantation, Simultaneous pancreas-kidney transplantation; HUS, Hemolytic Uremic Syndrome; AA, Aplastic anemia; SSINS, steroid sensitive idiopathic nephrotic syndrome; UC, ulcerative colitis; IBD, inflammatory bowel disease; Retro, retrospective; Pro, prospective; NR, not reported.