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Pharmacokinetic properties of the reference and candidate drugs. %HOA: Percentage of Human Oral Absorption; QPPCaco2: intestinal permeability in nm/s; QPPMDCK: renal permeability in nm/s; QPlogKHSA: Binding to human serum albumin; CNS: Central Nervous System activity; QPlogBB: brain/blood partition coefficient; PSA: Van der Waals surface area of polar nitrogen and oxygen atoms.
