Table 2.

Selective antibodies used to stain C5b-9 in human kidneys.

Name	Clonality	Source	Binding
			C5	C6	C7	C8	C9	Poly-C9	Incomplete C5b-9a	Soluble C5b-9	Membrane-bound C5b-9	Ref.
ab55811	Polyclonal	Rabbit	Unkn.	Unkn.	Unkn.	Unkn.	Unkn.	Unkn.	Unkn.	Unkn.	Unkn.	(53, 54)
aE11 or M0777	Monoclonal	Mouse	–	–	–	–	±	+	+	+	+	(46, 51)
Anti-C5b-9(m)	Polyclonal	Rabbit	–	–	–	–	–	Unkn.	Unkn.	+	+	(55, 56)
Anti-MAC	Polyclonal	Rabbit	–	–	–	–	–	Unkn.	Unkn.	+	+	(57)
Anti-MAC-neo	Polyclonal	Rabbit	–	–	–	–	–	Unkn.	+	+	+	(52)
bC5 or A239	Monoclonal	Mouse	–	–	–	–	±	+	±	+	+	(46)
B7	Monoclonal	Mouse	–	–	–	–	±	+	Unkn.	+	+	(58, 59)
Kolb 1975b	Polyclonal	Rabbit	–	–	–	–	–	Unkn.	+	+	+	(50)
PolyC9-MA	Monoclonal	Mouse	–	–	Unkn.	–	–	+	–	Unkn.	+	(44)
WU-7,2	Monoclonal	Mouse	–	–	–	–	±	–	Unkn.	+	+	(48, 60)
WU-13,15	Monoclonal	Mouse	Unkn.	–	–	Unkn.	±	–	–	+	+	(48, 60)
X197	Monoclonal	Mouse	Unkn.	Unkn.	Unkn.	–	+	+	–	Unkn.	+	(47, 49)
Xia 1988b	Monoclonal	Mouse	–	–	–	–	–	Unkn.	Unkn.	+	+	(61, 62)
3B1	Monoclonal	Mouse	–	–	–	–	–	+	–	+	+	(45)
1B4	Monoclonal	Unkn.	Unkn.	Unkn.	Unkn.	Unkn.	–	+	Unkn.	+	+	(63)

All antibodies against C5b-9 used for staining of C5b-9 in the included original studies, as specified per study in Supplementary Table 1 , are indicated. References to studies on their binding selectivity are given.

^aIncomplete forms of C5b-9 without C9, either soluble or membrane-bound, commonly referred to as C5b-6, C5b-7, and C5b-8.

^bNames used in Supplementary Tables 1 and 2 for antibodies without a specific name.

–, no binding; ±, weak binding; +, strong binding; poly-C9, polymerized C9; unkn., unknown.