Table 3.
Breakdown of QuantiFERON-TB Gold In-Tube assay indeterminate results and lymphopenia by immunomodulatory therapy
| Therapy | Patients, n/N (%) | ||
|---|---|---|---|
| Indeterminate results | Lymphopenia | Indeterminate results with lymphopenia | |
| Dimethyl fumarate | 21/61 (34.4) | 29/61 (47.5) | 17/21 (81.0) |
| Other treatments | 1/6 (16.7)a | 3/6 (50.0) | 1/1 (100)a |
| Fingolimod | 1/13 (7.7)a | 12/13 (92.3) | 1/1 (100)a |
| Injectables | 1/37 (2.7)a | 3/35 (8.6) | 1/1 (100)a |
| No therapy | 4/84 (4.8) | 2/84 (2.4) | None |
| Natalizumab | 0/10 | 0/10 | None |
| Anti-CD20 therapy | 0/10 | 0/10 | None |
a
Patients in these groups with indeterminate results with lymphopenia had been previously treated with dimethyl fumarate.