Fig. 1.

Pearson correlation matrix showing associations of G3+RIL with modality, mean brain dose (MBD), and volumes irradiated. Numbers in the boxes are correlation coefficients. G3+RIL was most strongly associated with V20 (volume receiving 20 Gy[RBE] or higher), and, to a somewhat lesser extent, with other volumes. Similarly, treatment modality was strongly associated with lower dose volumes but the association weakens as the dose increases. V20 is associated to varying degrees with all other volumes. In other words, if V20 is larger, then other volumes would be as well.