Table 1. Hub genes for hypomethylated, highly expressed genes ranked in cytoHubba.
| Catelogy | Rank methods in cytoHubba | |||||
| MCC | MNC | Degree | EPC | Closedness | Radiality | |
| Gene symbol top 15 | SPP1 | SPP1 | SPP1 | SPP1 | SPP1 | PECAM1 |
| VWF | VWF | VWF | VWF | VWF | SPP1 | |
| PECAM1 | PECAM1 | PECAM1 | COL1A1 | PECAM1 | VWF | |
| CDH5 | COL1A1 | COL1A1 | PECAM1 | EDN1 | EDN1 | |
| TEK | EDN1 | CDH5 | EDN1 | COL1A1 | COL1A1 | |
| EDN1 | CDH5 | EDN1 | DCN | CDH5 | CDH5 | |
| ANGPT1 | COL3A1 | DCN | CDH5 | DCN | MMP7 | |
| COL1A1 | DCN | COL3A1 | MMP1 | MMP7 | DCN | |
| SPARCL1 | FOS | MMP1 | COL3A1 | MMP1 | MMP1 | |
| CP | MMP1 | FOS | MMP7 | CAV1 | CAV1 | |
| GPC3 | TEK | TIMP3 | COMP | COL3A1 | COL3A1 | |
| CHRDL1 | THBS2 | SPARCL1 | THBS2 | FOS | FOS | |
| WFS1 | TIMP3 | CAV1 | TEK | A2M | ANGPT1 | |
| GOLM1 | MMP7 | A2M | ANGPT1 | ANGPT1 | TEK | |
| COL3A1 | COMP | TEK | TIMP3 | TEK | A2M | |