Table 4. Changes of differential metabolites in the aging and the constipation groups.

No.	Fecal metabolites	Aging	Constipation
1	2-oxoglutarate	↓	-
2	Acetate	↑	↑
3	Acetoacetate	↑	-
4	Acetone	↓	-
5	Alanine	↓	↓
6	α-xylose	↑	↑
7	Arginine	-	↑
8	Asparagine	↓	↓
9	Aspartate	↓	↓
10	Butyrate	-	↑
11	Carnitine	-	↑
12	Choline	↑	↑
13	Citrate	↓	↓
14	Creatinine	↓	↓
15	Ethanol	-	↑
16	Glucose	↓	↑
17	Glutamate	↓	↓
18	Isoleucine	↓	↓
19	Lactate	↑
20	Leucine	↓	↓
21	Lysine	↓	-
22	Methionine	↓	↓
23	Phenylalanine	↓	↑
24	Proline	↑	↓
25	Pyruvate	↓	↓
26	Scyllo-Inositol	↓	-
27	Taurine	-	↑
28	Threonine	↑	-
29	Trimethylamine-N-oxide	-	↑

“-”: Not changed;

as compared to control group, “↑”: increased; “↓”: decreased.