Figure 5.

miR-132 downregulates the expression of GSK-3β and GSK-3β in injured HT-22 cells in vitro. (A) The relative cell viability is nearly 60% under 200 μM H₂O₂, which contributes to the cellular stress state. (B) The expression levels of GSK-3β among 5 groups of different concentrations H₂O₂. (C) miR-132 potentially reverses the upregulated levels of GSK-3β under H₂O₂ treatment. (D) miR-132 potentially reverses the upregulated levels of GSK-3β under the AGEs treatment. *, **, and *** means P < 0.05, < 0.01, < 0.001 vs Con, n = 3 for each group.