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. 2020 Sep 12;8(1):81–90. doi: 10.1093/nop/npaa059

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© The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Neuro-Oncology and the European Association of Neuro-Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Task performance and brain activity measures of healthy controls (HC, solid line) and glioma patients (GLIOMA, dashed line) are presented here for the 0-back (0B) and the 2-back (2B) condition. Age-corrected results are presented by showing results for the mean age of all participants (mean age = 45.6 years). A, The percentage of incorrect responses (false alarms and missed targets combined) are shown (± SEM) for each group. Taking age into account, glioma patients showed reduced task performance compared to HCs. C and D, Signal change within the central executive network (CEN, C), and the default mode network (DMN, D) are shown (± SEM). Note the similar increase in activity within the CEN for HCs and glioma patients with increasing task difficulty. For the DMN, patients show reduced deactivation during 2B.