Age, mean (SD), y |
51.1 (14.3) |
Sex (male), n (%) |
50 (62) |
Marital status (married), n (%) |
64 (79) |
KPS, n (%), % |
|
100 |
38 (47) |
90 |
22 (27) |
≤ 80 |
21 (26) |
BMI, mean (SD) |
26.9 (5.4) |
Smoking, n (%) |
|
Current |
5 (6) |
Previous |
27 (33) |
Never |
30 (37) |
Alcohol consumption (regular/occasional), n (%) |
36 (44) |
Clinical variables |
All patients (n = 81) |
Brain tumor type, n (%) |
|
Primary |
74 (91) |
Grade IV |
39 (53) |
Grade III |
15 (20) |
Grade II |
17 (23) |
Other |
3 (4) |
Metastatic |
7 (9) |
Primary site (lung/breast) |
4 (57) |
Brain lesions (≥ 2) |
6 (86) |
Location, n (%) |
|
Frontal |
23 (28) |
Temporal |
20 (25) |
Parietal |
13 (16) |
Occipital |
2 (3) |
Multiple |
17 (21) |
Other |
6 (7) |
Laterality, n (%) |
|
Left |
39 (49) |
Right |
31 (39) |
Bilateral |
10 (13) |
Midline |
1 (1) |
Time since diagnosis, median (range), mo |
12 (1-383) |
Recurrence, n (%) |
21 (26) |
Progression in past 2 mo, n (%) |
12 (15) |
Treatment history, n (%) |
|
Surgery |
75 (93) |
Biopsy only |
9 (11) |
Radiation |
37 (46) |
Chemotherapy |
49 (61) |
Radiation with concurrent chemotherapy |
50 (62) |
Other |
4 (5) |
No. of symptoms reported by clinician, n (%) |
|
0 |
50 (62) |
1 |
16 (20) |
2 |
8 (10) |
3+ |
7 (9) |
History of psychological disorders |
7 (9) |
Type of common symptoms, n (%, of those presenting symptoms, n = 31) |
|
Lethargy |
11 (36) |
Headache |
9 (29) |
Mood disturbance |
6 (19) |
Nocturnal urinary and neurological deficits |
5 (16) |
Involuntary movement |
4 (13) |
Medications |
All patients (n = 81) |
Medication for complications related to cancer, n (%) |
|
Anticonvulsant |
44 (54) |
Antiemetic |
29 (36) |
Chemotherapy |
35 (43) |
Corticosteroid |
20 (25) |
Antidepressant |
5 (6) |
Benzodiazepine |
8 (10) |
PPI |
12 (15) |
Medication for comorbid illness, n (%) |
21 (26) |