Table 1.
Characteristics of 291 Patients With Low-Grade Glioma
| Factors | No. (%) |
|---|---|
| Total patients | 291 |
| Median age at first surgery, y | 40 |
| Median age at first MRI, y | 39 |
| Male | 158 (54%) |
| Histologic classification, WHO 2007 | |
| Oligodendroglioma | 137 (47%) |
| Astrocytoma | 61 (21%) |
| Oligoastrocytoma | 74 (25%) |
| NOS | 19 (7%) |
| Integrated classification, WHO 2016 | |
| Oligodendroglioma, IDH-mutated, 1p/19q codeleted | 92 (36%) |
| Diffuse astrocytoma, IDH-mutated, 1p/19q intact | 109 (43%) |
| Diffuse astrocytoma, IDH wild-type | 53 (21%) |
| Not tested | 37 (NA) |
| Tumor location | |
| Temporal and insula | 74 (25%) |
| Non-temporal (frontal, parietal, and occipital lobes) | 196 (67%) |
| Other (midline and deep structures, brainstem, and cerebellum) | 21 (7%) |
| Patients with preoperative seizures | 197 (68%) |
| With postoperative seizures | 143 (73%) |
| Without postoperative seizures | 54 (27%) |
| Patients with postoperative seizures | 183 (63%) |
| With preoperative seizures | 143 (78%) |
| Without preoperative seizures | 40 (22%) |
| Patients with intractable seizures | 120 (41%) |
| Seizure types | |
| Generalized onset | 81 (41%) |
| Focal onset | 79 (40%) |
| Focal onset with secondary generalization | 23 (12%) |
| Unclear semiology | 14 (7%) |
| Types of surgery | |
| Gross total resection/lobectomy | 41 (14%) |
| Subtotal resection | 128 (44%) |
| Biopsy | 120 (42%) |
| Undetermined | 2 (NA) |
Abbreviations: IDH, isocitrate dehydrogenase; NA, not applicable; NOS, not otherwise specified; WHO, World Health Organization.