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| Part A. Test characteristics (relative positive fractions compared with 3 ≤ PSA < 10) for reflex thresholds 1ng/mL, 1.5ng/mL and 2ng/mL | ||||||
| Disease state | Reflex test threshold | |||||
| 1ng/mL | (95% CI) | 1.5ng/mL | (95% CI) | 2ng/mL | (95% CI) | |
| Benign | 0.56 | (0.46–0.65) | 0.52 | (0.44–0.60) | 0.48 | (0.40–0.55) |
| GS = 6 | 0.83 | (0.74–0.93) | 0.79 | (0.72–0.87) | 0.72 | (0.66–0.80) |
| GS≥7 | 1.00 | – | 0.98 | (0.94–1.03) | 0.95 | (0.91–0.99) |
| CI: Confidence interval; GS: Gleason score; Source: [13] | ||||||
