Table 1. Representative candidate regions under selection in cat breeds with likely phenotype related candidate genes.
| Breed | Chr. | Start (Mb) | End (Mb) | Region size (Mb) | No. genes | Candidate gene(s) | Phenotype |
|---|---|---|---|---|---|---|---|
| Perisan1 | A2 | 101.75 | 103 | 1.25 | 8 | DLX6, DLX5 | Brachycephaly |
| C1 | 163.25 | 164.75 | 1.5 | 6 | DLX2 | ||
| Maine Coon | A1 | 188.25 | 189.25 | 1 | 4 | GABRG2, GABRA1, GABRA6, GABRB2 | Eating behavior/size |
| Bengal1 | D2 | 79.5 | 81.25 | 1.75 | 13 | FGFR2 | Coat type |
| Turkish Van | E3 | 43.75 | 44.75 | 1 | 48 | CLCN72 | Van color |
| American Curl | E3 | 41.25 | 44.75 | 3.75 | 123 | MCRIP2 | Curled ears |
| F1 | 63.5 | 45 | 1.25 | 6 | PBX13 | ||
| La Perm | B1 | 147.25 | 151 | 3.75 | 26 | EPGN, EREG | Curly coat |
| Ragdoll1 | A1 | 82 | 89 | 7 | 40 | LAMP1 | Multiple |
| Birman1 | B4 | 11.25 | 114 | 2.75 | 8 | KITLG | Gloves |
| Oriental | D3 | 1.25 | 2.25 | 1 | 5 | ADGRD1 | Body weight |
| Siamese | D3 | 1.25 | 2.25 | 1 | 5 | ADGRD1 | Body weight |
1 Candidate regions were found completely or partially shared among two populations (n = 25 cats each) of the same breed.
2 Due to the low density of SNPs on Chr.E3, flanking regions to the candidate region were explored. Candidate gene (CLCN7) is located upstream of the region at ~ 43.3Mb.
3 Due to low density of SNPs on Chr.F1, flanking regions were explored. Candidate gene (PBX1) is located upstream of the region at ~ 63Mb.