Table 2. Neonatal baseline characteristics of included studies on the effects of therapeutic hypothermia on death among asphyxiated neonates with hypoxic-ischemic encephalopathy.
| SR no | Authors | Year | Mean BW (g) HYPO: STD | GA (weeks) HYPO: STD | Apgar score HYPO: STD | Moderate NE (n–%) HYPO: STD | Severe NE (n–%) HYPO: STD |
|---|---|---|---|---|---|---|---|
| 1. | Lin et al. [28] | 2006 | 3310: 3430 | 38.7: 39.1 | 3:3 | 16: 15 | 7: 6 |
| 2. | Zhou et al. [29] | 2010 | 3360: 3299 | NA: NA | NA: NA | 41: 41 | 38: 35 |
| 3. | Akisu et al. [20] | 2013 | 3410: 3270 | 39.3: 39.1 | 4.3: 4.1 | 7: 5 | 3:3 |
| 4. | Robertson et al. [30] | 2008 | 3300: 3200 | 38: 38 | 4.7: 5.2 | 10: 10 | 6:1 |
| 5. | Thayyil et al. [31] | 2013 | 2977: 2890 | 38: 38.9 | 4.3: 4.5 | 6: 5 | 2:2 |
| 6. | Bharadwaj et al. [32] | 2012 | 2967: 2899 | 39.8: 40 | NA: NA | 5.34: 5.26 | 55:7 |
| 7. | Bhat et al. [33] | 2006 | NA: NA | NA: NA | NA: NA | NA:NA | NA:NA |
| 8. | Azzopardi et al. [21] | 2009 | 3450: 3350 | 40.3: 40.1 | 4:4: 4 | 65: 57 | 98: 95 |
| 9. | Jacobs et al. [34] | 2011 | NA: NA | NA: NA | NA: NA | NA: NA | NA:NA |
| 10. | Shankaran et al. [35] | 2005 | 3385: 3370 | NA: NA | NA: NA | 69: 66 | 32: 40 |
| 11. | Simbruner et al. [36] | 2010 | 3300: 3300 | 39.2: 39.4 | 3.4: 3.4 | 24: 17 | 38: 46 |
| 12. | Gluckman et al. [37] | 2005 | 3399: 3504 | 38.9: 39.1 | NA: NA | NA: NA | NA:NA |
| 13. | Zhou et al. [29] | 2010 | 3360: 3299 | NA: NA | NA: NA | 41: 41 | 38: 35 |
| 14. | Eicher et al. [38] | 2005 | 3241: 3550 | 38.8: 39.1 | NA: NA | 5:5 | 25: 25 |
| 15. | Battin et al. [39] | 2003 | 3333: 3371 | 40: 39.8 | 5: 5 | NA: NA | NA:NA |
| 16. | Shankaran et al. [40] | 2002 | NA: NA | NA: NA | NA: NA | NA: NA | NA:NA |
| 17. | Joy et al. [41] | 2012 | 2840: 2910 | NA: NA | 3.81: 3.45 | 51:9 | 7:7 |
| 18. | Maoulainine et al. [42] | 2017 | 3336: 3300 | NA: NA | NA: NA | NA: NA | NA:NA |
| 19. | Laptook et al. [43] | 2018 | 3379: 3303 | 39:39 | 4.2: 4.3 | 73: 78 | 10:7 |
| 20. | Gane et al. [44] | 2013 | 2792: 2903 | NA: NA | 3: 3 | 44: 45 | 15: 16 |
| 21. | Selway et al. [45] | 2010 | NA: NA | NA: NA | NA: NA | NA: NA | NA: NA |
| 22. | Susan et al. [34] | 2011 | 3348: 3515 | 3939.2 | 3: 3 | 63: 54 | 30: 29 |
| 23. | Jose et al. [46] | 2018 | 3259: 3278 | NA: NA | NA: NA | 51: 39 | 22: 28 |
| 24. | Azzopardi et al. [47] | 2014 | 3467: 3351 | 40.3: 40.1 | NA: NA | 62: 57 | 83: 78 |
| 25. | Shankaran, et al. [48] | 2012 | 3172: 3555 | NA: NA | NA: NA | 28: 41 | 15: 16 |
| 26. | Battin, et al. [49] | 2001 | 3333: 3458 | 39.5: 39.4 | 5: 5 | NA: NA | NA:NA |
| 27. | Gane, et al. [44] | 2013 | 2792: 2903 | NA: NA | 3: 3 | 45: 44 | 15: 16 |
| 28. | Namasivayam et al. [43] | 2017 | NA: NA | NA: NA | NA: NA | NA: NA | NA:NA |