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. 2021 Feb 25;15(2):e0009146. doi: 10.1371/journal.pntd.0009146

Table 2. Number of people requiring post-exposure prophylaxis (PEP) to reduce the new case detection (NCD) by 50% and by 90% at global level and in the three country groups.

50% reduction 90% reduction
NCD at time 0 Duration (years) NCD People requiring PEP (million) Duration (years) NCD People requiring PEP (million)
Mean Rangea Mean Rangea Mean Rangea Mean Rangea
Global 228,970 5 107,520 48,970–152,290 20.6 11.9–29.9 22 21,400 4,800–44,690 40.2 19.8–64.8
Group 1b 188,430 5 86,780 47,360–131,970 16.8 10.3–24.3 22 17,770 4,570–36,180 32.9 17.3–52.0
Group 2c 30,450 6 13,680 4,730–24,070 3.2 1.3–5.1 21 3,030 260–7,080 5.4 1.9–9.5
Group 3d 10,080 6 4,520 1,470–8,080 1.0 0.4–1.7 21 990 60–2,310 1.8 0.6–3.1

a 95% confidence interval reflecting the stochastic variation of 1,000 runs

b India, Brazil, and Indonesia

c DR Congo, Ethiopia, Nepal, Bangladesh, Myanmar, Tanzania, Sri Lanka, Madagascar, Philippines, Nigeria, Mozambique, Ivory Coast, South Sudan, Egypt, Sudan, Angola, Comoros, Kiribati, Micronesia

d 88 remaining countries