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. 2021 Feb 25;15(2):e0009146. doi: 10.1371/journal.pntd.0009146

Table 4. Number of people requiring post-exposure prophylaxis (PEP) to reduce the new case detection (NCD) by 50% and by 90% in high and low-endemic states in India, Brazil and Indonesia.

50% reduction 90% reduction
Country NCD at time 0 Duration (years) NCD People requiring PEP (million) Duration (years) NCD People requiring PEP (million)
Mean Rangea Mean Rangea Mean Rangea Mean Rangea
India High 107,097 5 47,660 23,650–73,580 9.1 5.3–13.4 22 10,700 2,000–21,930 18.0 8.8–29.1
Low 28,388 4 13,520 3,530–26,480 2.0 0.7–3.6 20 2,490 0–6,810 4.3 1.0–8.5
Brazil High 28,749 6 12,950 9,910–16,480 4.1 3.3–5.0 21 2,710 1,550–3,920 7.9 5.8–10.0
Low 7,344 5 3,650 2,010–5,540 1.6 0.9–2.3 19 720 180–1,370 3.3 1.7–5.1
Indonesia High 14,642 7 6,820 5,260–8,500 1.6 1.3–1.9 25 1,420 840–2,040 2.8 2.1–3.5
Low 2,214 6 1,040 280–1,900 0.2 0.1–0.4 22 210 0–510 0.4 0.1–0.7

a 95% confidence interval reflecting the stochastic variation of 1,000 runs