Table 2. Mean DSC for segmentation of all 97 subjects (dyslexic and control) before and after smoothing and normalization using GM tissue overlaps (mean ± SD).

Segmentation DSC index	LSTG	LOTG	LC	Mean
DSC (Input Image)	0.8124±0.0221	0.7315±0.0436	0.6219±0.0362	0.7321
DSC (normalized image with HMN method [16])	0.8249±0.0197	0.7367±0.0502	0.6424±0.0412	0.7532
DSC (normalized image with proposed MHN method)	0.8561±0.0183*	0.7511±0.0497*	0.6548±0.0338	0.7756*

*Statistically significantly larger than the other two (p-value<0.05); SD-standard deviation; LSTG-left superior temporal gyrus; LOTG-left occipital temporal gyrus; LC-lateral cerebellum; HMN-histogram matching normalization; MHN-modified histogram normalization.