Table 4. Mean segmented brain region volume for all 97 subjects (dyslexic and controls) before and after normalization (mean ± SD).
Gray matter volume in selected brain regions | LSTG | LOTG | LC |
---|---|---|---|
Volume (reference image) | 583.7±61* | 411.3±61* | 1098.8±133* |
Volume (input image) | 509.6±63 | 472.7±28 | 1082.4±134 |
Volume (normalized image with HMN method [16]) | 542.9±65 | 421.6±28 | 1077.3±130 |
Volume (normalized image with proposed MHN method) | 581.9±62* | 409.1±62* | 1093.6±135* |
*Statistically significantly larger than the other two (p-value<0.05); SD-standard deviation; LSTG-left superior temporal gyrus; LOTG-left occipital temporal gyrus; LC-lateral cerebellum; HMN-histogram matching normalization; MHN-modified histogram normalization.