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. 2021 Feb 25;16(2):e0245579. doi: 10.1371/journal.pone.0245579

Table 4. Mean segmented brain region volume for all 97 subjects (dyslexic and controls) before and after normalization (mean ± SD).

Gray matter volume in selected brain regions LSTG LOTG LC
Volume (reference image) 583.7±61* 411.3±61* 1098.8±133*
Volume (input image) 509.6±63 472.7±28 1082.4±134
Volume (normalized image with HMN method [16]) 542.9±65 421.6±28 1077.3±130
Volume (normalized image with proposed MHN method) 581.9±62* 409.1±62* 1093.6±135*

*Statistically significantly larger than the other two (p-value<0.05); SD-standard deviation; LSTG-left superior temporal gyrus; LOTG-left occipital temporal gyrus; LC-lateral cerebellum; HMN-histogram matching normalization; MHN-modified histogram normalization.