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. 2021 Feb 25;16(2):e0246830. doi: 10.1371/journal.pone.0246830

Table 2. Comparison of retinal nerve fiber layer and macular thickness measurements between metabolic syndrome patients and healthy controls.

OCT parameters Metabolic Syndrome (n = 113) Control (n = 118) P-value *
RNFL (Global, μm) 93.6 ± 9.9 99.0 ± 9.3 <0.001
RNFL (Superior, μm) 117.2 ± 16.0 126.3 ± 14.4 <0.001
RNFL (Inferior, μm) 124.5 ± 17.5 131.0 ± 16.4 0.002
RNFL (Nasal, μm) 67.2 ± 10.3 67.7 ± 9.5 0.70
RNFL (Temporal, μm) 65.5 ± 10.2 69.5 ± 9.8 0.002
CMT (μm) 237.0 ±14.0 243.6 ± 18.0 0.002
Parafoveal (Global, μm) 311.5 ± 17.6 315.4 ± 14.0 0.062
Parafoveal (Superior, μm) 316.0 ± 19.2 319.8 ± 17.2 0.2
Parafoveal (Inferior, μm) 307.8 ± 20.9 314.6 ± 14.6 0.004
Parafoveal (Nasal, μm) 318.1 ± 16.3 320.3 ± 15.9 0.3
Parafoveal (Temporal, μm) 303.6 ± 17.1 306.0 ± 18.9 0.32
Perifoveal (Global, μm) 274.2 ± 28.5 279.3 ± 11.9 0.07
Perifoveal (Superior, μm) 278.5 ± 18.5 282.6 ± 13.7 0.051
Perifoveal (Inferior, μm) 270.1 ± 18.0 270.5 ± 13.0 0.84
Perifoveal (Nasal, μm) 298.1 ± 14.1 300.7 ± 17.1 0.20
Perifoveal (Temporal, μm) 260.1 ± 12.8 262.0 ± 12.4 0.27

Data presented as mean ± SD,

* = unpaired t-test,

RNFL = retinal nerve fiber layer, CMT = central macular thickness.