Table 4. Performance of TranSynergy and DeepSyenrgy on leave cell out scenario and leave drug out scenario for the classification task.

Model	Leave cells out		Leave drugs out
	ROC-AUC	PR-AUC	ROC-AUC	PR-AUC
TranSynergy	0.808 ± 0.017	0.372 ± 0.022	0.778 ± 0.032	0.406 ± 0.106
DeepSynergy	0.805 ± 0.017	0.360 ± 0.022	0.753 ± 0.030	0.378 ± 0.075
Statistical significance (p-value)	0.3328	0.0908	0.0034	0.1379