Table 7. Examples of predicted synergistic novel drug pairs.
Drug combination | Cell line | Predicted Synergy score | Z-score |
---|---|---|---|
DEXAMETHASONE and ETOPOSIDE | CAOV3 | 94.520215 | 3.07259459 |
ETOPOSIDE and METFORMIN | CAOV3 | 70.556332 | 2.21009253 |
ETOPOSIDE and SN-38 | CAOV3 | 69.380475 | 2.16777138 |
DEXAMETHASONE and VINBLASTINE | OCUBM | 38.6095235 | 1.94930657 |
DEXAMETHASONE and PACLITAXEL | SKMES1 | 37.9697725 | 1.91635083 |
ETOPOSIDE and VINORELBINE | OV90 | 33.844834 | 1.89400207 |
PACLITAXEL and VINORELBINE | OV90 | 32.5451685 | 1.81387084 |
ETOPOSIDE and VINBLASTINE | CAOV3 | 56.799048 | 1.71494381 |
DEXAMETHASONE and VINBLASTINE | KPL1 | 37.8084735 | 1.6825975 |
ETOPOSIDE and PACLITAXEL | CAOV3 | 53.1252895 | 1.58271882 |