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. 2021 Feb 23;21(9):e290–e295. doi: 10.1016/S1473-3099(21)00048-7

Table 3.

Relationship between test performance, PPV, and NPV for asymptomatic people

Predictive values
Distribution of test outcomes among 10 000 people tested
PPV NPV True positive False positive True negative False negative
5% likelihood of testing positive
80% sensitivity, 97% specificity 58% 99% 400 285* 9215 100
80% sensitivity, 98% specificity 68% 99% 400 190* 9310 100
80% sensitivity, 99% specificity 81% 99% 400 95* 9405 100
90% sensitivity, 99% specificity 83% 99% 450 95* 9405 50
10% likelihood of testing positive
80% sensitivity, 97% specificity 75% 98% 800 270* 8730 200
80% sensitivity, 98% specificity 82% 98% 800 180* 8820 200
80% sensitivity, 99% specificity 90% 98% 800 90 8910 200
90% sensitivity, 99% specificity 91% 99% 900 90 8910 100

People at higher risk of acquiring or transmitting COVID-19 than the general population such as health-care workers, care home workers, and first responders. NPV=negative predictive value. PPV=positive predictive value.

*

Mitigation strategy is to confirm positives.