Table 2.
Fold increase data of PATRR DNA compared to background 6q26 in ChIP assays using DSB-associated antibodies γH2AX, Rad52 and NBS1 in peripheral blood lymphocytes
| γH2AX | Rad51 | NBS1 | |
|---|---|---|---|
| PATRR17 | 1.58 | 1.41 | 1.36 |
| PATRR8 | 1.20 | 1.03 | 1.33 |
| PATRR11 | 1.10 | 1.07 | 1.05 |
| PATRR22 | 1.25 | 1.16 | 1.21 |
| PATRR median | 1.20 | 1.15 | 1.21 |
| PATRR mean | 1.51 | 1.16 | 1.24 |
| P-value | 0.0002 | 0.0005 | 0.0086 |
Median values are reported for individual PATRRs. Data from all four PATRRs are combined to generate the total PATRR median and mean values for a given antibody. P-values are calculated for the total PATRR value for each antibody using the one-sample t-test comparing the total PATRR to the mean value of 1 using GraphPad Software at www.graphpad.com.