Table 3.
DigiGait parameters of 12-week-old females
| Parameters (41 in total) | Unit | NT vs C9–500 | NT vs C9–800 | C9–500 vs C9–800 |
|---|---|---|---|---|
| Significant Parameters (Desired FDR = 5%) | (real#) | 6 | 9 | 12 |
| Swing | (s) | ns | * * * * P < 0.0001 | * * * * P < 0.0001 |
| Swing/Stride | (%) | ns | * * P = 0.0052 | * P = 0.0176 |
| Brake | (s) | ns | ns | ns |
| Brake/Stride | (%) | ns | ns | ns |
| Propel | (s) | ns | ns | * P = 0.0255 |
| Propel/Stride | (%) | ns | ns | ns |
| Stance | (s) | * P = 0.0444 | ns | * * P = 0.0020 |
| Stance/Stride | (%) | ns | * * P = 0.0052 | * P = 0.0174 |
| Stride | (s) | ns | * * * * P < 0.0001 | * * * * P < 0.0001 |
| Brake/Stance | (%) | ns | ns | ns |
| Propel/Stance | (%) | ns | ns | ns |
| Stance/Swing | (real#) | ns | * P = 0.0134 | ns |
| Stride Length | (cm) | ns | * * * * P < 0.0001 | * * * * P < 0.0001 |
| Stride Frequency | (steps/s) | * P = 0.0292 | * * * P = 0.0001 | * * * * P < 0.0001 |
| Paw Angle | (deg) | ns | ns | ns |
| Absolute Paw Angle | (deg) | ns | ns | ns |
| Paw Angle Variability | (deg) | ns | ns | ns |
| Stance Width | (cm) | * P = 0.0292 | ns | ns |
| Step Angle | (deg) | ns | ns | ns |
| Stride Length Variability | (cm) | ns | ns | ns |
| Stance Width Variability | (cm) | * * P = 0.059 | ns | ns |
| Step angle Variability | (deg) | ns | ns | * P = 0.0283 |
| #Steps | (real#) | ns | ns | ns |
| Stride Length CV | (CV%) | * * * * P < 0.0001 | * * * * P < 0.0001 | ns |
| Stance Width CV | (CV%) | * * * P = 0.0006 | ns | * P = 0.0243 |
| Step Angle CV | (CV%) | ns | ns | * P = 0.0202 |
| Swing Duration CV | (CV%) | ns | ns | ns |
| Paw Area at Peak Stance | (cm2) | ns | ns | ns |
| Paw Area Variability at Peak Stance | (cm2) | ns | ns | ns |
| Hind Limb Shared Stance Time | (s) | ns | ns | ns |
| Shared/Stance | (%) | ns | ns | ns |
| Stance Factor | (real#) | ns | ns | ns |
| Gait Symmetry | (real#) | ns | * * * P = 0.0001 | * * * * P < 0.0001 |
| MAX dA/dT | (cm2/s) | ns | ns | ns |
| MIN dA/dT | (cm2/s) | ns | ns | ns |
| Tau—Propulsion | (real#) | ns | ns | ns |
| Overlap Distance | (cm) | ns | ns | ns |
| Paw Placement Positioning | (cm) | ns | ns | ns |
| Ataxia Coefficient | (real#) | ns | ns | ns |
| Midline Distance | (cm) | ns | ns | ns |
| Paw Drag | (mm2) | ns | ns | ns |
#, number; CV, coefficient of variation; ns, not significant in one-way ANOVA; desired FDR (false discovery rate) set to 5%; NT n = 44; C9–500 n = 38; C9–800 n = 24.