Table 1. ASS diagnostic criteria (adapted from Witt et al. 2016)*.

*[2]

ASS: antisynthetase syndrome; tRNA: transfer ribonucleic acid

Connors et al. (2010)	Solomon et al. (2011)
Required: presence of anti-aminoacyl tRNA synthetase antibody	Required: presence of anti-aminoacyl tRNA synthetase antibody
PLUS one or more of the following clinical features: Raynaud’s phenomenon, arthritis, interstitial lung disease, fever (not attributable to another cause), mechanic’s hands (thickened and cracked skin on hands, particularly at fingertips)	PLUS two major/one major and two minor criteria:
	Major	Minor
	Interstitial lung disease (not attributable to another cause), polymyositis or dermatomyositis as per Bohan and Peter criteria	Arthritis, Raynaud’s phenomenon, mechanic’s hands