Table 1. ASS diagnostic criteria (adapted from Witt et al. 2016)*.
Connors et al. (2010) | Solomon et al. (2011) | |
Required: presence of anti-aminoacyl tRNA synthetase antibody | Required: presence of anti-aminoacyl tRNA synthetase antibody | |
PLUS one or more of the following clinical features: Raynaud’s phenomenon, arthritis, interstitial lung disease, fever (not attributable to another cause), mechanic’s hands (thickened and cracked skin on hands, particularly at fingertips) | PLUS two major/one major and two minor criteria: | |
Major | Minor | |
Interstitial lung disease (not attributable to another cause), polymyositis or dermatomyositis as per Bohan and Peter criteria | Arthritis, Raynaud’s phenomenon, mechanic’s hands |