Table 2.
Latencies and side bias in behavioral experiments
| Cohort | Correct latency | Incorrect latency | Magazine latency | Side bias (left) |
|---|---|---|---|---|
| Experiment 1 Pre-acquisition | ||||
| Visual discrimination | ||||
| Sham 5,7-DHT |
4334 ± 327 3493 ± 193* |
4266 ± 256 3324 ± 175* |
1816 ± 74 1571 ± 63* |
48.36 ± 1.97 44.99 ± 1.30 |
| Reversal 1 | ||||
| Sham 5,7-DHT |
4137 ± 534 2625 ± 126* |
4027 ± 540 2630 ± 132* |
1703 ± 83 1454 ± 60* |
44.50 ± 4.38 44.52 ± 1.74 |
| Reversal 2 | ||||
| Sham 5,7-DHT |
3805 ± 551 2669 ± 149* |
3853 ± 598 3223 ± 329* |
1710 ± 96 1446 ± 49* |
43.96 ± 2.11 46.19 ± 1.68 |
| Experiment 2 Postacquisition | ||||
| Retention | ||||
| Sham 5,7-DHT |
3565 ± 317 3689 ± 365 |
6337 ± 2915 4592 ± 756 |
1590 ± 101 1828 ± 129 |
52.46 ± 1.58 47.72 ± 2.51 |
| Reversal 1 | ||||
| Sham 5,7-DHT |
3795 ± 314 3864 ± 628 |
4074 ± 395 4196 ± 828 |
1605 ± 111 1707 ± 74 |
48.87 ± 2.39 51.19 ± 1.85 |
| Reversal 2 | ||||
| Sham 5,7-DHT |
3422 ± 214 2936 ± 271 |
3736 ± 356 3876 ± 1074 |
1554 ± 101 1640 ± 81 |
45.50 ± 3.76 50.70 ± 2.28 |
| Experiment 3 Local depletions | ||||
| Visual discrimination | ||||
| Sham OFC mPFC |
4340 ± 439 5489 ± 461 5724 ± 690** |
4359 ± 452 5411 ± 525 4987 ± 372*** |
1595 ± 50 1626 ± 61 1546 ± 46 |
50.34 ± 2.47 49.19 ± 2.64 46.80 ± 2.58 |
| Reversal 1 | ||||
| Sham OFC mPFC |
3543 ± 253 3507 ± 175 4761 ± 339** |
3590 ± 233 3555 ± 148 5201 ± 264*** |
1564 ± 47 1726 ± 90 1645 ± 85 |
46.62 ± 2.25 47.19 ± 3.82 44.14 ± 4.87 |
| Reversal 2 | ||||
| Sham OFC mPFC |
3406 ± 134 3669 ± 538 4785 ± 363** |
3355 ± 148 3694 ± 526 4897 ± 343*** |
1586 ± 60 1647 ± 94 1562 ± 54 |
46.33 ± 2.41 45.98 ± 2.83 43.52 ± 5.77 |
Notes: All data are shown as mean ± SE; latencies are in milliseconds and side bias as percentage of bias arbitrarily to the left side on the screen. *P < 0.05, main effect of lesion in a two-way ANOVA; **P < 0.05, ***P < 0.01, LSD post hoc mPFC versus Sham after significant main effect of lesion detected in a two-way ANOVA.