Figure 2.

(a) Clustering dendrogram of differentially expressed genes associated with systemic sclerosis-related pulmonary arterial hypertension (SSc-PAH). (b) Network heat map in the coexpression module (as the color deepened, the overlap gradually increased). (c) Heat map of the correlation between module eigengenes and clinical traits of systemic sclerosis-related pulmonary arterial hypertension. (d) Distribution of average gene significance and errors in the modules related to systemic sclerosis-related pulmonary arterial hypertension. (e) The gene significance for systemic sclerosis-related pulmonary arterial hypertension in the turquoise module (one dot represents one gene in the turquoise module). (f) The top 16 genes with high gene significance for sclerosis-related pulmonary arterial hypertension were tightly related to each other. PAH: pulmonary arterial hypertension.